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Sexual preference chemical found in mice

first_imgHealthLifestyle Sexual preference chemical found in mice by: – March 24, 2011 Tweet 33 Views   no discussions Share Sharing is caring!center_img Share Share A chemical in the brain controls sexual preference in mice, according to scientists in China.Male mice bred without serotonin lose their preference for females, a report in Nature says.The researchers say it is the first time that a neurotransmitter has been shown to play a role in sexual preference in mammals.Experts have warned about the dangers of drawing conclusions about human sexuality.The research team first bred male mice whose brains were not receptive to serotonin.A series of experiments demonstrated that these mice had lost the preference for females shown by unmodified males.When presented with a choice of partners, they showed no overall preference for either males or females.When just a male was introduced into the cage, the modified males were far more likely to mount the male and emit a “mating call” normally given off when encountering females than unmodified males were.Similar results were achieved when a different set of mice were bred. These lacked the tryptonphan hydroxylase 2 gene, which is needed to produce serotonin.However, a preference for females could be “restored” by injecting serotonin into the brain.The report concludes: “Serotonergic signalling is crucial for male sexual preference in mice. This is the first time, to our knowledge, that a neurotransmitter in the brain has been demonstrated to be important in mammalian sexual preference.”HumansSexual behaviour in mice is thought to be driven by their sense of smell.Professor Keith Kendrick, a neuroscientist at the Babraham Institute in Cambridge, said: “In terms of having potential relevance to understanding human sexual preference/orientation, we are of course far less influenced by odour cues in this context than mice are.“There is some very limited evidence for altered responses to selective serotonin uptake inhibitors (SSRIs) in the brains of homosexuals, but we have been using psychoactive drugs which either increase or decrease serotonin function for quite some time now, and while effects on sexual arousal, impulsivity and aggression have often been reported, no effects on sexual preference/orientation have.“At this time therefore any potential links between serotonin and human sexual preferences must be considered somewhat tenuous.”Source: BBC Newslast_img read more


Red Bank School Superintendent to Retire at End of Month

first_imgRED BANK – Superintendent of Public Schools Dr. Laura Morana has submitted notice to the school board that she will retire at the end of the month.Morana was in her eighth year with the district. Her last day will be Sept. 30.The timing of her retirement is unusual in that it is occurring at the start of the school year. Her announcement was not included on the board’s posted agenda.When asked about the timing, board President Ben Forest declined to comment calling it a “personnel matter.”He said Morana had informed the board prior to her public announcement.During Wednesday’s board meeting the board began setting up a strategy to replace Morana. “We are going as quickly as we can to find a replacement for Dr. Morana. In the meantime, we will be looking for an interim superintendent.”Forest said it is expected that the district will hire an interim superintendent from outside the district.“The board is pleased with the legacy and record that Dr. Morana has left us,” Forest said. “The board gave her an ovation last night.”Red Bank Mayor Pasquale Menna said he was “saddened to see Laura go. But at the same time I am extraordinarily grateful that she has been able to devote seven years of her life to Red Bank and in that time brought a level of excellence and accomplishment that had never been experienced by us in the past.“Dr. Morana raised the bar and challenged students, parents and guardians, teachers, administrators and staff to achieve new levels of excellence.  For that I am thankful,” Menna said..last_img read more


South Okanagan halts Bomber winning streak

first_imgHowever, poor weather made the pitch unplayable forcing coaches to cancell the game.The teams will meet this week in West Kootenay High School Fieldhockey League play on Thursday in Castlegar, at 4:30 p.m. at Pass Creek.The West Kootenay zones are set for October 23 at Pass Creek.The winner advanced to the B.C. High School AA Girl’s Fieldhockey Championships in West Vancouver.Meanwhile the LVR Junior Bombers scored a pair of wins over Rossland and South Okanagan.Emma Borhi scored a hat-trick to pace LVR to a 5-1 win over Rossland.Emma Wheeldon added two goals for LVR.Jena Wheeldon and Andrea Stinson are the last Bombers to register three goals in a game.Saturday, the Bombers continued to rock on offence, shutting out South Okanagan 5-0.Borhi scored twice while Naomi Perkins, Chiara Chirico and Ava Strautman added singles. The L.V. Rogers Bombers suffered its first loss of the 2013 High School Fieldhockey season as South Okanagan Hornets of Oliver scored a 3-1 victory in the West Kootenay Tourney this past weekend at Pass Creek pitch in Castlegar.Naomi Perkins scored the lone goal for the Bombers in the five-team tourney.”This was a very good side,” said coach Val Gibson.The Bombers opened the tourney Friday by drawing 2-2 against host Stanley Humphries Rockers of Castlgar.Sarah Wade scored twice to lead the Bomber offence while Allie Zondervan added a pair of assists.The contest marked the first time Bomber keeper Tara Yowek has allowed two goals in a game.Saturday the Bombers were scheduled to play the J. Lloyd Crowe Hawks.last_img read more


Crooked Scientists Get Rehab

first_imgFor those who trust scientists, it may come as a shock that some bad apples are getting rehab.Violations of scientific ethics have skyrocketed over the last decade.  Plagiarism, falsifying data, outright fraud – these and other examples of ethical breaches have produced some notable scandals.  What should be done?  Nature on January 8 reported about a new program to rehabilitate the bad apples:With the rapid growth of misconduct cases, some scientists are worried that preventative training in research ethics might not be enough. Nor will it be possible simply to dismiss all violators from science. Scientific rehabilitation, they say, will have to become a necessary tool for research-integrity offices.This seems to be a new problem.  The US Office of Research Integrity received double the complaints from 2011 last year.  Why is that?  It’s another question, not addressed in the article.  The focus is on whether rehab works, and whether bad scientists deserve a second chance.The hero of the article is James Dubois (Saint Louis University), who is trying to make saints out of sinners with his nifty RePAIR program (Restoring Professionalism and Integrity in Research). “We believe that if we can equip them with certain skills, they can return to the field as very productive individuals,” he said.  Through information, informal discussions and management programs, he processes his students and funnels them back into the mainstream with a certificate of completion to potentially fool their managers.No conflict of interest there.  Dubois’ program has a $500,000 grant behind it from the National Institutes of Health, and Dubois charges $3,000 per penitent.  Let’s hope when Dubois teaches about “self-serving biases” on day one, he does it righteously.  A program like this might have more credibility if it were taught by a volunteer or a respected clergyman known for his integrity.For more articles on scientific misconduct, search on “fraud” or peruse the category “Politics and Ethics”.We hope rehab works with some, but isn’t it just like liberals to prefer rehab over punishment?  Some of Dubois’ inmates may have misappropriated thousands of taxpayer dollars, ruined others’ reputations, or garnered fame from fraud.  Dubois believes the really bad apples are only 10-15% of the ones caught.  “There there, Dr. Liar, let’s just have a group chat session to see why you committed that crime.  You couldn’t help it; it was your selfish genes.  Darwin made you do it.”What these scientists need is repentance and conversion.  Give skills to a crook, and you make him a more skillful crook.  Some of the graduates of RePAIR could easily fake penitence then take the information they gathered back to the lab, having learned how better to avoid getting caught.  Without a genuine change of heart, why not?  Dubois is not teaching repentance.  He seems to be building self-esteem.This story underscores the need for righteousness in science.  As with any other field of human endeavor, science cannot work without honest practitioners.  You cannot trust any conclusion from a scientific enterprise that condones (or doesn’t recognize) unethical behavior.  Science requires honesty and integrity—eternal values that cannot evolve.  There’s only one world view that can defend a foundation for true ethical behavior; the Judeo-Christian world view. (Visited 27 times, 1 visits today)FacebookTwitterPinterestSave分享0last_img read more


Water Quality Status Report issued by Ohio Farm Bureau

first_imgShare Facebook Twitter Google + LinkedIn Pinterest Addressing the challenges that threaten Ohio’s clean water resources is an important priority for the agriculture community. The Ohio Farm Bureau Federation (OFBF) has released a report detailing its efforts to ensure safe and healthy water for the state.The Water Quality Status Report provides a list of action items being taken by farmers, Farm Bureau and many collaborative partners to implement new farming techniques and best practices to protect water while farming productively. It emphasizes actions in the Western Lake Erie Basin (WLEB), but water quality is a statewide issue and Farm Bureau is addressing it throughout the state. Farm Bureau also has established statewide partnerships to identify comprehensive solutions to complex water issues.“Normally, water is something we all take for granted, unless we have too much of it or not enough,” said Steve Hirsch, OFBF president. “Water quality and quantity has always been important to farmers, but they are also vital to the quality of life for all Ohioans.”The Toledo water crisis and the recent algae bloom events in Lake Erie and Grand Lake St. Mary’s prompted swift action by OFBF’s Board of Trustees to make sure that farmers in the major watersheds were doing their part to help to protect water quality in Ohio, thus creating the Water Quality Action Plan.“We committed over $1 million of our member funds to water quality efforts,” Hirsch said. “We have also been encouraging farmers throughout the state and especially within the Western Lake Erie Basin to comply with Senate Bill 150 to complete their fertilizer applicator certification 2 years ahead of the 2017 state law requirement and then to go above and beyond that requirement to create a nutrient management plan for their farms.”Ohio’s largest farm organization is also increasing their commitment to Healthy Water Ohio, a statewide coalition of water users, business groups and environmental interests that are creating a strategic plan for water over the next 20 to 30 years in Ohio.Greg LaBarge, an Ohio State Extension Agronomy Field Specialist, has been very involved with outreach and educational efforts for Ohio farmers. Ohio State’s College of Food, Agriculture and Environmental Sciences has a long history of working with farmers on natural resource and environmental issues such as Ohio’s water quality. One of the latest outreach efforts is a program called “Field to Faucet.”“This effort is taking a very close look at what we are doing from an agricultural standpoint and looking at the watershed in total, through the stream system and into Lake Erie’s Western Basin”, LaBarge said. “We are also thinking about what is happening to the water as it reenters the systems for citizens to use.”Education is another aspect to cleaner water in The Buckeye State.“With Senate Bill 150, a new program focusing on fertilizer applicator certification was developed,” LaBarge said. “Since September of 2014, we have trained 6,429 people across the state in 110 different meetings in all 88 counties. That effort will be ongoing as we work to meet that 2017 state law deadline.”The collaboration of the state’s agricultural organizations with The Ohio State University and Ohio Soil and Water Conservation Districts is something that Farm Bureau Executive Vice President, Jack Fisher, is very proud to highlight.“There has been a lot of work done when it comes to water quality, but there is a lot more to do and it will take a lot of time to do it,” Fisher said. “As we solve one or two things, more things may be brought to our attention and those issues will be added to our list to find solutions to. This is a big, complex issue and it will take time.”There will also be the challenge of finding the balance between improving the water in Ohio and producing enough grains and oilseed to not only keep farms profitable, but to also feed an ever-growing population.“Let’s not forget that as we talk about water quality and water management, we also take for granted food and food production,” Fisher said. “So as we go forward, our policy initiatives in water quality and food production have to be in collaboration and not in isolation.”last_img read more


A Pari Maa in the rough and tumble of politics

first_imgPramila Bisoi, a social worker from the nondescript Cheramaria village in Odisha, is fast spreading her wings as the Pari Maa (Fairy Mother) of the masses in the Aska parliamentary constituency, from where she is contesting as a Biju Janata Dal candidate.For the past five decades, this 68-year-old woman has been helping in safe delivery and proper care of newborns in her village. “Even 50-year-olds in our village call her Pari Maa in reverence,” says her nephew Arabind Bisoi. At public meetings in Purishottampur and Patapur earlier this week, crowds kept up the chants of Pari Maa all through. Ms. Bisoi, however, never utters a word against her opponents while campaigning. “I am a mother to all. How can I be against anyone just for elections?” she asks. “My greatest strength is that winning or losing has no meaning for me, I am just enjoying the responsibility given to me by Naveen Patnaik,” she says.Married off at the age of five and forced to leave school, Ms. Bisoi has been working towards social emancipation of women in her village ever since her days as a teenaged bride. “It all started with sanitation and women’s health during childbirth. Later I became the leader of a Women’s Self-Help Group and the local Van Surakshya Samity,” she reveals.Ms. Bisoi was cooking midday meal for students of a primary school in her village when she received a call from the BJD headquarters asking her to reach Bhubaneswar. Getting a party ticket for the Aska Lok Sabha seat came as a real surprise to her. But CM Naveen Patnaik had taken into account her organisational capacity among women. She is the secretary of WSHGs in Aska block. “Earlier I was only working for the women of my area. But with the blessings of Mr. Patnaik, I have taken up the responsibility of 70 lakh women linked to WSHGs under the ‘Mission Shakti’ programme in Odisha,” she says.Around 140 members of 14 WSHGs in Cheramaria are her regular campaign partners now. Wherever she goes for campaigning, hundreds of women reach out to greet her. Ms. Bisoi is facing a triangular fight in the Aska seat, where voting will take place on April 18. Her main opponents are CPI’s Ramkrushna Panda and BJP’s Anita Subhadarshini.last_img read more


ONE: Iniong looking for decisive win over Yamaguchi

first_imgMOST READ Typhoon Kammuri accelerates, gains strength en route to PH Kris Aquino ‘pretty chill about becoming irrelevant’ Japan’s Mei Yamaguchi (L) and Philippines’ Gina Iniong face off during the ONE Championship press conference at Marina Bay in Singapore. INQUIRER PHOTO/ Sherwin VardeleonREAD: ONE: Yamaguchi eyes quick revenge vs Filipino bet Iniong So the Baguio City native is looking for a more decisive outcome this time in their upcoming atomweight bout on Friday, and she is careful not to make the same mistakes this time around.“I will go for a TKO if I could,” said Iniong, a veteran wushu artist, who sees her striking game as her biggest edge. “But this is mixed martial arts, and anything can happen. So let’s see.”ADVERTISEMENT Seniors Dennison, Trinidad grateful to Racela for Season 80 Don’t miss out on the latest news and information. ONE: Iniong looking for decisive win over Yamaguchi314 viewsSportsVentuno Web Player 4.51 Stronger peso trims PH debt value to P7.9 trillion Read Next Kammuri turning to super typhoon less likely but possible — Pagasa LATEST STORIES View comments QC cops nab robbery gang leader, cohort For her part, Yamaguchi has gone 8-5 since with her latest win an impressive submission of Jenny Huang in June.READ: Two weeks after last fight, Iniong faces Yamaguchi in ONE Singapore cardFEATURED STORIESSPORTSWATCH: Drones light up sky in final leg of SEA Games torch runSPORTSSEA Games: Philippines picks up 1st win in men’s water poloSPORTSMalditas save PH from shutout“Since our last fight, I think I’ve improved a lot. In a scale of 1-10, maybe my improvement is at eight,” the soft-spoken Iniong told PH-based reporters after the ONE: Immortal Pursuit press conference at Marina Bay Sands here.Iniong, who was a last-minute replacement for Angela Lee in the 10-bout card set at Singapore Indoor Stadium, edged Yamaguchi in a split decision victory in May 2014, a result the Japanese fighter’s camp thought was debatable. SINGAPORE—Both Gina Iniong and Mei Yamaguchi have grown as fighters in the three and half years since they last faced off.Iniong has made name for herself as one of the top pound-for-pound fighters in the region and one of the fast rising female fighters in the ONE Championship promotion with two convincing wins just this year.ADVERTISEMENT Trending Articles PLAY LIST 00:50Trending Articles00:58ONE: Iniong looking for decisive win over Yamaguchi00:50Trending Articles01:37Protesters burn down Iran consulate in Najaf01:47Panelo casts doubts on Robredo’s drug war ‘discoveries’01:29Police teams find crossbows, bows in HK university01:35Panelo suggests discounted SEA Games tickets for students02:49Robredo: True leaders perform well despite having ‘uninspiring’ boss02:42PH underwater hockey team aims to make waves in SEA Games Brace for potentially devastating typhoon approaching PH – NDRRMC CPP denies ‘Ka Diego’ arrest caused ‘mass panic’ among S. Tagalog NPA Japan ex-PM Nakasone who boosted ties with US dies at 101last_img read more


Shane Warne, Liz Hurley promote apparel brand ‘Spinners’

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More woe for injury-ravaged Welbeck

first_imgArsenal More woe for Welbeck as injury-ravaged Arsenal forward hobbles off against Watford Chris Burton Last updated 2 years ago 02:10 10/15/17 FacebookTwitterRedditcopy Comments(0) Danny Welbeck Arsenal Watford 141017 Getty Arsenal Watford v Arsenal Watford Premier League The England international was forced off after an hour against the Hornets, with his unfortunate fitness issues continuing to hold him back Danny Welbeck’s injury woes continue at Arsenal, with the England forward forced off against Watford.The 26-year-old was brought back into the fold by Arsene Wenger for the game at Vicarage Road after suffering a groin problem in his last outing against Chelsea.Arsenal 6/1 to win Europa League Article continues below Editors’ Picks Why Barcelona god Messi will never be worshipped in the same way in Argentina Lyon treble & England heartbreak: The full story behind Lucy Bronze’s dramatic 2019 Liverpool v Man City is now the league’s biggest rivalry and the bitterness is growing Megan Rapinoe: Born & brilliant in the U.S.A. That injury ruled him out for a month and forced him to miss the concluding World Cup qualifiers against Slovenia and Lithuania.He was to last just an hour upon his return to action before limping from the field with a muscle complaint to be replaced by Mesut Ozil.That’s all for today from @DannyWelbeck, who limps off to be replaced by @MesutOzil1088Welcome back, Mesut#WFCvAFC 0-1 (60) pic.twitter.com/Z9hBZNFxm5— Arsenal FC (@Arsenal) October 14, 2017Welbeck has struggled with fitness issues throughout his time with the Gunners since joining from Manchester United in 2014.He was forced to miss the 2015 FA Cup final after picking up an injury, with that problem eventually keeping him out for 10 months.Another problem then kept him out of Euro 2016 with England, with another eight months spent on the sidelines.It remains to be seen how serious his latest knock is, but Welbeck will be cursing his luck as he fails to add continuity and consistency to his game.last_img read more


Gundogan back to his brilliant BVB best

first_imgManchester City The resurrection of Gundogan: Man City man back to his brilliant Borussia Dortmund best Sam Lee Last updated 1 year ago 00:06 2/17/18 FacebookTwitterRedditcopy Comments(6) Ilkay Gundogan Manchester City Getty Images Manchester City İ. Gündoğan Premier League Guardiola Yaya Touré Kevin De Bruyne Raheem Sterling Leroy Sané Sergio Agüero The midfielder’s progress was severely hampered by a serious knee injury but he is steadily getting back to his best, and there could be more to come Twenty games, or around 2000 minutes. That’s the amount of game time Ilkay Gundogan needed to get back to his best.Speaking at the start of December, Marti Perarnau, the author who charted Pep Guardiola’s time at Bayern Munich with incredible detail, declared that Gundogan was “not in good shape,” but that the midfielder “could arrive in March and April at a very good level” if he were to play roughly 20 matches over Christmas and beyond.AdChoices广告“He’s not fit, he’s not in good shape,” Perarnau told the 93:20 podcast. “But he understands very well the tempo of the play that the team needs at each moment, like David Silva. Article continues below Editors’ Picks Lyon treble & England heartbreak: The full story behind Lucy Bronze’s dramatic 2019 Liverpool v Man City is now the league’s biggest rivalry and the bitterness is growing Megan Rapinoe: Born & brilliant in the U.S.A. A Liverpool legend in the making: Behind Virgil van Dijk’s remarkable rise to world’s best player “I think he needs 20 more matches in his legs. He hasn’t played too many matches in the last three years.“I hope in 20 matches we will see a very good Gundogan.”He has played in 17 games since that interview, a rough total of 1,150 minutes, and the evidence suggests Perarnau was right.Gundogan’s two-goal, man-of-the-match performance against Basel in midweek was a reminder of the form he was starting to produce last season, before a serious knee injury forced him to miss roughly 10 of his 18 months as a City player.”I love to play for this club, for this manager, with these team-mates, it’s just fun,” Gundogan said after the game in Switzerland. “Every single guy understands, is feeling it, and can see it that we have a very special group, with a very special atmosphere.”Gundogan quoteHe is finally starting to play his role in that group, the role expected of him when he signed from Borussia Dortmund in 2016.After all, he was the very first signing of the Guardiola era, designed to be come in and help the Catalan impose his fast passing style in English football. As Perarnau notes, Gundogan understands the flow of a game just as David Silva does.But, thanks to his injury, in his 18 months in Manchester he has only fleetingly shown his best qualities.The German’s first period at City, between his belated debut on September 14, 2016 and injury exactly three months later, had as many highs as it did lows. Standing in for either David Silva or Kevin De Bruyne, he dovetailed well with whichever man he played alongside, helping to establish City’s possession game. He even chipped in with doubles against Barcelona and West Brom, his knack for arriving in the box at the right moment surprising even those who had watched him closely in the Bundesliga.But Guardiola, perhaps too confident in his side’s ability, was ramping up his tactical plans during this period, attempting to play all three of his creative midfielders at once, with Fernandinho and a three-man defence behind them. The Blues managed to dominate possession but as a result of failures elsewhere the experiment rarely looked convincing. In truth, none of the three midfielders looked at their best, either.So much so that when Gundogan was ruled out for the season, in the very first game after Guardiola simplified his plans after a bruising defeat at Leicester, it was seen, in the coldest terms, a blessing in disguise: with an uncomplicated back four in place, Gundogan’s injury also deprived Guardiola of the temptation to cram three creative midfielders into the same line-up.Gundogan quoteGuardiola had worked out how to control games with just De Bruyne and Silva by the time Gundogan returned last September, and thanks to their performances and his own physical limitation, the German had to wait for his opportunities.He was handed his first start in the EFL Cup in September, but a nasty kick to the ankle hampered his progress and he did not start again for five weeks.Since then, the end of October, he has often been called upon to stand in for Silva.No City player, going back to when Silva first signed for the club in 2010, has managed to fill the Spaniard’s boots sufficiently, but Gundogan has shown that he can do a fine job; against Napoli away and Spurs at home he helped pull the strings of impressive 4-2 and 4-1 victories respectively.Those were open, fast-paced games but Gundogan also proved he can unlock tighter contests. Replacing De Bruyne, he provided two clever assists in two minutes to turn an FA Cup tie with Burnley on its head.Gundogan can suffer by being compared to his two influential team-mates – his failure to find “the last pass” in the recent draw at Burnley seemed worse because it is easily imagined that Silva would have delivered it – but he would probably walk into any other midfield in the country on current form.Gundogan quoteAnd certainly when he gets those 2000 minutes under his belt. With key fixtures in all four competitions coming up in the next few weeks, he appears to be hitting form at exactly the right time.Other players are also returning from injuries and Gundogan, as predicted by Perarnau, looks set to have a key role in the final months of what could be a record-breaking season.“The team needs a very good Gundogan,” Perarnau added. “I think he can be at his highest level if he plays 20, 25 matches in December, January and February. He could arrive in March and April at a very good level. I think the team will need Gundogan.”Sources close to Guardiola’s staff have intimated this week that he is finally back to his Dortmund best, but that level of performance could merely be a temporary pit-stop; given how most of his team-mates have progressed under Guardiola’s tutelage, you get the feeling that Gundogan’s very best is still to come.last_img read more